PF-06726304
Cat. No.:YN310068
CAS No. :1616287-82-1
产品名称: | PF-06726304 |
CAS No.: | 1616287-82-1 |
Chemical Name: | |
Synonyms: | PF-6726304 |
分子量: | 446.33 |
分子式: | C₂₂H₂₁Cl₂N₃O₃ |
SMILES: | O=C1N(CC2=C(C)C=C(C)NC2=O)CCC3=C1C(Cl)=C(C4=C(C)ON=C4C)C=C3Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PF-06726304 是一种有效的选择性EZH2抑制剂。PF-06726304 抑制野生型和 Y641N 突变型 EZH2,Ki分别为 0.7 和 3.0 nM。PF-06726304 具有强效的抗肿瘤生长活性。 |
IC50和靶点: | [{name:"EZH2 WT:0.7 nM (Ki)"},{name: "EZH2 Y641N:3.0 nM (Ki)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |