UNC0321
Cat. No.:YN310104
产品名称: | UNC0321 |
CAS No.: | 1238673-32-9 |
Chemical Name: | |
Synonyms: | UNC 0321; UNC-0321, UNC0321; UNC-0321 |
分子量: | 515.69 |
分子式: | C₂₇H₄₅N₇O₃ |
SMILES: | CN1CCC(NC2=C3C=C(OC)C(OCCOCCN(C)C)=CC3=NC(N4CCN(C)CCC4)=N2)CC1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | UNC0321 是一种有效的选择性组蛋白甲基转移酶G9a抑制剂,Ki为 63 pM,IC50值为 6-9 nM。UNC0321 还抑制GLP,IC50值为 15-23 nM。UNC0321 对 SET7/9,SET8/PreSET7,PRMT3 和 JMJD2E 无活性。 |
IC50和靶点: | [{name:"EHMT1/GLP/KMT1D:15-23 nM (IC50)"},{name: "G9a:63 pM (Ki)"},{name: "G9a:6-9 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |