GSK3368715 dihydrochloride
Cat. No.：YN310194
CAS No. ：1628925-77-8
| 产品名称: | GSK3368715 dihydrochloride |
| CAS No.: | 1628925-77-8 |
| Chemical Name: | |
| Synonyms: | EPZ019997 dihydrochloride |
| 分子量: | 439.46 |
| 分子式: | C₂₀H₄₀Cl₂N₄O₂ |
| SMILES: | CNCCN(CC1=CNN=C1C2CCC(COCC)(COCC)CC2)C.Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) 是具有口服活性的，可逆的，SAM 非竞争性 I 型蛋白精氨酸甲基转移酶(PRMTs)抑制剂 (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8))。GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) 导致精氨酸甲基化状态的转变 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
