UNC 0631
Cat. No.：YN310248
CAS No. ：1320288-19-4
| 产品名称: | UNC 0631 |
| CAS No.: | 1320288-19-4 |
| Chemical Name: | N-[1-(cyclohexylmethyl)-4-piperidinyl]-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy] 4-quinazolinamine |
| Synonyms: | UNC0631 |
| 分子量: | 635.93 |
| 分子式: | C₃₇H₆₁N₇O₂ |
| SMILES: | COC1=CC2=C(NC3CCN(CC4CCCCC4)CC3)N=C(N5CCN(C(C)C)CCC5)N=C2C=C1OCCCN6CCCCC6 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | UNC 0631 是一种有效的组蛋白甲基转移酶G9a抑制剂，IC50值为 4 nM。UNC 0631 有效降低 MDA-MB-231 细胞中H3K9me2的水平，IC50为 25 nM。 |
| IC50和靶点: | [{name:"G9a:4 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Liu, F., Barsyte-Lovejoy, D., Allali-Hassani, A., et al.Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolinesJ. Med. Chem.54(17),6139-6150(2011)
