BRD9539
Cat. No.：YN310273
CAS No. ：1374601-41-8
| 产品名称: | BRD9539 |
| CAS No.: | 1374601-41-8 |
| Chemical Name: | 2-(benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid |
| Synonyms: | BRD9539; BRD 9539; BRD-9539. |
| 分子量: | 399.44 |
| 分子式: | C₂₄H₂₁N₃O₃ |
| SMILES: | O=C(C1=CC=C2C(N=C(NC(C3=CC=CC=C3)=O)N2CCCC4=CC=CC=C4)=C1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BRD9539 是一种组蛋白甲基转移酶G9a抑制剂，IC50为 6.3 μM。BRD9539 还抑制PRC2活性，并且对 SUV39H1，NSD2 和 DNMT1 无活性。 |
| IC50和靶点: | [{name:"G9a:6.3 μM (IC50)'}, 'PRC2'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Yuan, Y., Wang, Q., Paulk, J., et al.A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinomaACS Chem. Biol.7(7),1152-1157(2012)
