AMI-1
Cat. No.:YN310310
CAS No. :20324-87-2
产品名称: | AMI-1 |
CAS No.: | 20324-87-2 |
Chemical Name: | |
Synonyms: | Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate);7,7'-(Carbonyldiimino)bis(4-hydroxy-2-naphthalenesulfonic acid) disodium salt;AMI-1;SODIUM 6,6'-(1,3-UREYLENE)BIS(1-NAPHTHOL-3-SULFONATE);disodium 4-hydroxy-7-[(5-hydroxy-7-sulfonato-2- |
分子量: | 548.45 |
分子式: | C₂₁H₁₄N₂Na₂O₉S₂ |
SMILES: | O=C(NC1=CC2=CC(S(=O)(O[Na])=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)(O[Na])=O)=CC(O)=C4C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | AMI-1 是一种有效的,细胞渗透性的,可逆的蛋白精氨酸 N-甲基转移酶 (PRMTs) 抑制剂,对人 PRMT1 和酵母 Hmt1p 作用的IC50值分别为 8.8 μM 和 3.0 μM。AMI-1 通过阻断肽-底物结合对 PRMTs 发挥抑制作用。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |