BAY-598
Cat. No.：YN310324
CAS No. ：1906919-67-2
| 产品名称: | BAY-598 |
| CAS No.: | 1906919-67-2 |
| Chemical Name: | (S,Z)-N-(1-(N'-cyano-N-(3-(difluoromethoxy)phenyl)carbamimidoyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl)-N-ethyl-2-hydroxyacetamide |
| Synonyms: | BAY-598;(S,E)-N-(1-(N'-cyano-N-(3-(difluoromethoxy)phenyl)carbamimidoyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl)-N-ethyl-2-hydroxyacetamide;BAY 598 - Bio-X;BAY598;GTPL8953;BAY 598;BDBM50180955;J3.601.000B;Q27074893;(S)-N-(1-(N'-Cyano-N-(3-(dif |
| 分子量: | 525.34 |
| 分子式: | C₂₂H₂₀Cl₂F₂N₆O₃ |
| SMILES: | ClC1=C(Cl)C=CC(C2=NN(/C(NC#N)=N/C3=CC=CC(OC(F)F)=C3)C[C@@H]2N(C(CO)=O)CC)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BAY-598 是SMYD2的一个选择性小分子抑制剂，其IC50值为 27 nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Eggert, E., Hillig, R.C., Koehr, S., et al.Discovery and characterization of a highly potent and selective aminopyrazoline-based in vivo probe (BAY-598) for the protein lysine methyltransferase SMYD2J. Med. Chem.59(10),4578-4600(2016)
