BCI-121
Cat. No.:YN310334
CAS No. :432529-82-3
产品名称: | BCI-121 |
CAS No.: | 432529-82-3 |
Chemical Name: | 4-(aminocarbonyl)-N-(4-bromophenyl)-1-piperidineacetamide |
Synonyms: | BCI-121,BCI 121,BCI121 |
分子量: | 340.22 |
分子式: | C₁₄H₁₈BrN₃O₂ |
SMILES: | NC(C1CCN(CC(NC2=CC=C(Br)C=C2)=O)CC1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | BCI-121是能够抑制癌症细胞增殖的SMYD3抑制剂。 |
IC50和靶点: | |
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Peserico, A., Germani, A., Sanese, P., et al.A SMYD3 small-molecule inhibitor impairing cancer cell growthJ. Cell. Physiol.230(10),2447-2460(2015)
Wang, Y., Xie, B.-H., Lin, W.-H., et al.Amplification of SMYD3 promotes tumorigenicity and intrahepatic metastasis of hepatocellular carcinoma via upregulation of CDK2 and MMP2Oncogene38(25),4948-4961(2019)