Daminozide
Cat. No.：YN310234
| 产品名称: | Daminozide |
| CAS No.: | 1596-84-5 |
| Chemical Name: | 1-(2,2-dimethylhydrazide)-butanedioic acid |
| Synonyms: | 丁酰肼 |
| 分子量: | 160.17 |
| 分子式: | C₆H₁₂N₂O₃ |
| SMILES: | O=C(NN(C)C)CCC(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Daminozide 是一种植物生长调节剂，是人类KDM2/7组蛋白脱甲基酶的选择性抑制剂，对PHF8，KDM2A和KIAA1718的IC50值分别为 0.55，1.5 和 2.1 μM。与测试的其他脱甲基酶亚家族成员相比，Daminozide 对 KDM2/7 亚家族具有 >100倍的选择性。 |
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Rose, N.R., Woon, E.C.Y., Tumber, A., et al.Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylasesJ. Med. Chem.55(14),6639-6643(2012)
Armitage, A.M., Bergmann, B., and Bell, E.L.Effect of daminozide and light intensity on growth and flowering of calendula as a potted plantHortScience22(4),611-612(1987)
