I-OMe-Tyrphostin AG 538
Cat. No.：YN440280
CAS No. ：1094048-77-7
规格
价格(RMB)
库存
| 产品名称: | I-OMe-Tyrphostin AG 538 |
| CAS No.: | 1094048-77-7 |
| Chemical Name: | |
| Synonyms: | I-OMe-AG 538 |
| 分子量: | 437.19 |
| 分子式: | C₁₇H₁₂INO₅ |
| SMILES: | N#C/C(C(C1=CC=C(O)C(O)=C1)=O)=C\C2=CC(OC)=C(O)C(I)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) 是IGF-1R激酶的特异性抑制剂。I-OMe-Tyrphostin AG 538 抑制 IGF-1R 介导的信号传导，并优先对营养缺乏的 PANC1 细胞产生细胞毒性。I-OMe-Tyrphostin AG 538 是具有 ATP 竞争性的PI5P4Kα抑制剂，IC50为 1 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
