Kira8
Cat. No.：YN290146
CAS No. ：1630086-20-2
| 产品名称: | Kira8 |
| CAS No.: | 1630086-20-2 |
| Chemical Name: | (S)-2-Chloro-N-(6-methyl-5-((3-(2-(piperidin-3-ylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)naphthalen-1-yl)benzenesulfonamide |
| Synonyms: | AMG-18 |
| 分子量: | 601.12 |
| 分子式: | C₃₁H₂₉ClN₆O₃S |
| SMILES: | O=S(C1=CC=CC=C1Cl)(NC2=C3C=CC(C)=C(OC4=NC=CC=C4C5=NC(N[C@@H]6CNCCC6)=NC=C5)C3=CC=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Kira8 (AMG-18) 是一种单选择性IRE1α抑制剂，可以变构减弱IRE1α RNase活性，IC50为 5.9 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Harringhton, P.E., et. al.: ACS Med. Chem. Lett., (2014)
