Moxonidine
Cat. No.:YN321469
产品名称: | Moxonidine |
CAS No.: | 75438-57-2 |
Chemical Name: | 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine |
Synonyms: | 莫索尼定; BDF5895 |
分子量: | 241.68 |
分子式: | C₉H₁₂ClN₅O |
SMILES: | CC1=NC(OC)=C(NC2=NCCN2)C(Cl)=N1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Moxonidine(BDF5895)是咪唑啉1型受体(I1-R)选择性激动剂,为降压剂。 |
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Munk, S.A., Lai, R.K., Burke, J.E., et al.Synthesis and pharmacologic evaluation of 2-endo-amino-3-exo-isopropylbicyclo[2.2.1]heptane: a potent imidazoline1 receptor specific agentJ. Med. Chem.39(6),1193-1195(1996)
Ernsberger, P., Haxhiu, M.A., Graff, L.M., et al.A novel mechanism of action for hypertension control: moxonidine as a selective I1-imidazoline agonistCardiovasc. Drugs Ther.8(Suppl 1),27-41(1994)