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Moxonidine

Cat. No.:YN321469

  • CAS No. :75438-57-2

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    • 参考文献
    • 产品名称: Moxonidine
      CAS No.: 75438-57-2
      Chemical Name: 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine
      Synonyms:莫索尼定; BDF5895
      分子量:241.68
      分子式:C₉H₁₂ClN₅O
      SMILES:CC1=NC(OC)=C(NC2=NCCN2)C(Cl)=N1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Moxonidine(BDF5895)是咪唑啉1型受体(I1-R)选择性激动剂,为降压剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Munk, S.A., Lai, R.K., Burke, J.E., et al.Synthesis and pharmacologic evaluation of 2-endo-amino-3-exo-isopropylbicyclo[2.2.1]heptane: a potent imidazoline1 receptor specific agentJ. Med. Chem.39(6),1193-1195(1996)

      Ernsberger, P., Haxhiu, M.A., Graff, L.M., et al.A novel mechanism of action for hypertension control: moxonidine as a selective I1-imidazoline agonistCardiovasc. Drugs Ther.8(Suppl 1),27-41(1994)

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