Trimethobenzamide hydrochloride
Cat. No.：YN250401
| 产品名称: | Trimethobenzamide hydrochloride |
| CAS No.: | 554-92-7 |
| Chemical Name: | N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxy-benzamide, monohydrochloride |
| Synonyms: | Ro 2-9578 |
| 分子量: | 424.92 |
| 分子式: | C₂₁H₂₉ClN₂O₅ |
| SMILES: | O=C(NCC1=CC=C(OCCN(C)C)C=C1)C2=CC(OC)=C(OC)C(OC)=C2.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trimethobenzamide hydrochloride 是多巴胺D2受体阻断剂，可用作预防恶心和呕吐的止吐剂。 |
| IC50和靶点: | |
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Smith, H.S., Cox, L.R., and Smith, B.R.Dopamine receptor antagonistsAnn. Palliat. Med.1(2),137-142(2012)
Shallek, W., Heise, G.A., Keith, E.F., et al.Anti-emetic activity of 4-(2-dimethylaminoethoxy)-N-(3,4,5-trimethoxybenzoyl) benzylamine hydrochlorideJ. Pharmacol. Exp. Ther.126(3),270-277(1959)
Dhawan, B.N., Saxena, P.N., and Gupta, G.P.Antagonism of apomorphine-induced pecking in pigeonsBr. J. Pharmacol. Chemother.16(2),137-145(1961)
Peppard, S.B.Effect of drug therapy on compensation from vestibular injuryLaryngoscope96(8),878-898(1986)
