N-Glycolylneuraminic acid
Cat. No.:YN250421
产品名称: | N-Glycolylneuraminic acid |
CAS No.: | 1113-83-3 |
Chemical Name: | N-(2-hydroxyacetyl)-neuraminic acid |
Synonyms: | NeuGc; GcNeu |
分子量: | 325.27 |
分子式: | C₁₁H₁₉NO₁₀ |
SMILES: | O[C@@]1(O[C@H]([C@@H]([C@H](C1)O)NC(CO)=O)[C@@H]([C@@H](CO)O)O)C(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | N-Glycolylneuraminic acid 是一种非人唾液酸分子,是可以在猪中合成但在人类中不合成的。N-Glycolylneuraminic acid 作为结合甲型流感病毒 (IAVs) 的诱饵受体起作用。 |
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Nguyen, D.H., Tangvoranuntakul, P., and Varki, A.Effects of natural human antibodies against a nonhuman sialic acid that metabolically incorporates into activated and malignant immune cellsJ. Immunol.175(1),228-236(2005)
Hedlund, M., Padler-Karavani, V., Varki, N.M., et al.Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progressionProc. Natl. Acad. Sci. USA105(48),18936-18941(2008)