T-705RTP sodium
Cat. No.：YN250498
CAS No. ：356783-10-3
| 产品名称: | T-705RTP sodium |
| CAS No.: | 356783-10-3 |
| Chemical Name: | 6-?Fluoro-?3,?4-?dihydro-?4-?[5-?O-?[hydroxy[[hydroxy(ph?osphonooxy)?phosphinyl]?oxy]?phosphinyl]?-??-?D-?ribofuranosyl]?-?3-?oxo-?pyrazinecarboxamide Sodium Salt |
| Synonyms: | |
| 分子量: | 595.10 |
| 分子式: | C₁₀H₁₂FN₃Na₃O₁₅P₃ |
| SMILES: | O[C@H]1[C@H](N2C(C(C(N)=O)=NC(F)=C2)=O)O[C@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)[C@H]1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | T-705RTP sodium 是一种具有具有选择性和 GTP 竞争性的流感病毒 RNA 聚合酶 (RNA polymerase) 抑制剂，IC50为 0.14 μM，Ki为 1.52 μM。T-705RTP sodium 是 T-705 的活性三磷酸盐代谢产物，具有有效的抗流感病毒活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Egawa, H., et al.: PCT Int. Appl. (2001), WO 2001060834 A1 20010823
Egawa, H., et al.: Jpn. Kokai Tokkyo Koho (2004), JP 2004043371 A 20040212
