Cletoquine
Cat. No.：YN250501
| 产品名称: | Cletoquine |
| CAS No.: | 4298-15-1 |
| Chemical Name: | 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-ethanol |
| Synonyms: | Desethylhydroxychloroquine |
| 分子量: | 307.82 |
| 分子式: | C₁₆H₂₂ClN₃O |
| SMILES: | CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCNCCO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cletoquine (Desethylhydroxychloroquine) 是 Hydroxychloroquine 的主要活性代谢产物，是由 CYP2D6，CYP3A4，CYP3A5 和 CYP2C8 同工酶在肝脏中形成的。Cletoquine 也是一种 Chloroquine 衍生物，具有抗基孔肯雅热病毒 (CHIKV) 的能力。Cletoquine 具有抗疟作用，并可用于自身免疫性疾病的研究。 |
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Charlier, B., Pingeon, M., Dal Piaz, F., et al.Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole bloodBiomed. Chromatogr.32(8),e4258(2018)
