EIDD-2801
Cat. No.：YN250506
CAS No. ：2349386-89-4
| 产品名称: | EIDD-2801 |
| CAS No.: | 2349386-89-4 |
| Chemical Name: | uridine, 4-oxime, 5′-(2-methylpropanoate) |
| Synonyms: | Molnupiravir |
| 分子量: | 329.31 |
| 分子式: | C₁₃H₁₉N₃O₇ |
| SMILES: | O[C@@H]([C@H]([C@H](N1C(N/C(C=C1)=N/O)=O)O2)O)[C@H]2COC(C(C)C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | EIDD-2801 是核糖核苷类似物 EIDD-1931 的口服生物可利用的异丙酯前药。EIDD-2801 显示出广泛的抗流感病毒 (influenza virus) 和冠状病毒 (coronaviruses) 的活性，如SARS-CoV-2，MERS-CoV，SARS-CoV。EIDD-2801 有用于 COVID-19 和季节性，流行性流感的潜力。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Sheahan, T.P., Sims, A.C., Zhou, S., et al.An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in miceSci. Transl. Med.12(541),eabb5883(2020)
Toots, M., Yoon, J.-J., Cox, R.M., et al.Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epitheliaSci. Transl. Med.11(515),eaax5866(2019)
