Favipiravir
Cat. No.：YN250595
CAS No. ：259793-96-9
| 产品名称: | Favipiravir |
| CAS No.: | 259793-96-9 |
| Chemical Name: | 6-fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide |
| Synonyms: | 法匹拉韦; T-705 |
| 分子量: | 157.10 |
| 分子式: | C₅H₄FN₃O₂ |
| SMILES: | O=C(N)C1=NC(F)=CNC1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Favipiravir (T-705) 是一种病毒 RNA 聚合酶 (RNA polymerase) 抑制剂，可转变为其活性形式 Favipiravir-ribofuranosyl-5′-triphosphate (RTP)。Favipiravir-RTP 抑制流感病毒RNA依赖性的RNA聚合酶 (RdRP) 活性，IC50为 341 nM。 |
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Furuta, Y., Takahashi, K., Fukuda, Y., et al.In vitro and in vivo activities of anti-influenza virus compound T-705Antimicrob. Agents and Chemother.46(4),977-981(2002)
Furuta, Y., Takahashi, K., Shiraki, K., et al.T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infectionsAntiviral Res.82(3),95-102(2009)
Furuta, Y., Takahashi, K., Kuno-Maekawa, M., et al.Mechanism of action of T-705 against influenza virusAntimicrob. Agents and Chemother.49(3),981-986(2005)
