Nitazoxanide
Cat. No.:YN250951
CAS No. :55981-09-4
产品名称: | Nitazoxanide |
CAS No.: | 55981-09-4 |
Chemical Name: | 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-benzamide |
Synonyms: | 硝唑尼特; NTZ; NSC 697855 |
分子量: | 307.28 |
分子式: | C₁₂H₉N₃O₅S |
SMILES: | O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=CC=C2OC(C)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Nitazoxanide是抗原生动物化合物,对犬流感病毒的IC50为0.17 到 0.21μM。 |
IC50和靶点: | |
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de Carvalho, L.P.S., Lin, G., Jiang, X., et al.Nitazoxanide kills replicating and nonreplicating Mycobacterium tuberculosis and evades resistanceJ. Med. Chem.52(19),5789-5792(2009)
Theodos, C.M., Griffiths, J.K., D'Onfro, J., et al.Efficacy of nitazoxanide against Cryptosporidium parvum in cell culture and in animal modelsAntimicrob. Agents Chemother.42(8),1959-1965(1998)
Mostafa, A., Kandeil, A., Elshaier, Y.A.M.M., et al.FDA-approved drugs with potent in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2Pharmaceuticals (Basel)13(12),443(2020)
Rossignol, J.F., La Frazia, S., Chiappa, L., et al.Thiazolides, a new class of anti-influenza molecules targeting viral hemagglutinin at the post-translational levelJ. Biol. Chem.284(43),29798-29808(2009)