Dendrobine
Cat. No.：YN251508
| 产品名称: | Dendrobine |
| CAS No.: | 2115-91-5 |
| Chemical Name: | (2aS,4aS,5R,6S,7R,7aS,7bR)-decahydro-1,7b-dimethyl-6-(1-methylethyl)-7,5-(epoxymethano)-1H-cyclopent[cd]indol-9-one |
| Synonyms: | 石斛碱 |
| 分子量: | 263.38 |
| 分子式: | C₁₆H₂₅NO₂ |
| SMILES: | O=C1O[C@]2([H])[C@@H](C(C)C)[C@@]1([H])[C@@](CC3)([H])[C@]4(C)[C@@]3([H])CN(C)[C@]24[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dendrobine 是从Dendrobium nobile中分离出的一种生物碱。Dendrobine 对甲型流感病毒具有抗病毒活性，对A/FM-1/1/47 (H1N1)、A/Puerto Rico/8/34 H274Y (H1N1) 和 A/Aichi/2/68 (H3N2) 作用IC50值分别为3.39 μM、 2.16 μM 、5.32 μM。 |
| IC50和靶点: | |
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Meng, C.-W., He, Y.-L., Peng, C., et al.Picrotoxane sesquiterpenoids from the stems of Dendrobium nobile and their absolute configurations and angiogenesis effectFitoterapia121,206-211(2017)
Song, T.-H., Chen, X.-X., Lee, C.K.-F., et al.Dendrobine targeting JNK stress signaling to sensitize chemotoxicity of cisplatin against non-small cell lung cancer cells in vitro and in vivoPhytomedicine53,18-27(2019)
