Dehydroandrographolide
Cat. No.：YN251518
| 产品名称: | Dehydroandrographolide |
| CAS No.: | 134418-28-3 |
| Chemical Name: | 3E-[2-[(1S,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-2(3H)-furanone |
| Synonyms: | 脱水穿心莲内酯 |
| 分子量: | 332.43 |
| 分子式: | C₂₀H₂₈O₄ |
| SMILES: | C[C@@]([C@H]1C/C=C(C=CO2)/C2=O)(CC[C@H]3O)[C@@](CCC1=C)([H])[C@]3(C)CO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dehydroandrographolide 是从草药穿心莲中提取的。Dehydroandrographolide 通过使 iNOS 失活来降低 LPS 诱导的急性肺损伤中的氧化应激，并具有抗感染活性。 |
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Chen, H., Ma, Y.-B., Huang, X.-Y., et al.Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agentsBioorg. Med. Chem. Lett.24(10),2353-2359(2014)
Sui, Y., Wu, F., Lv, J., et al.Identification of the novel TMEM16A inhibitor dehydroandrographolide and its anticancer activity on SW620 cellsPLoS One10(12),e0144715(2015)
Che, D., Zheng, Y., Hou, Y., et al.Dehydroandrographolide targets CD300f and negatively regulated MRGPRX2-induced pseudo-allergic reactionPhytother. Res.36(5),2173-2185(2022)
