Chelidonine
Cat. No.：YN251596
| 产品名称: | Chelidonine |
| CAS No.: | 476-32-4 |
| Chemical Name: | 5bR,6S,7,12bS,13,14-hexahydro-13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol |
| Synonyms: | 白屈菜碱 |
| 分子量: | 353.37 |
| 分子式: | C₂₀H₁₉NO₅ |
| SMILES: | CN1[C@@]2([H])[C@@]([C@H](CC3=C2C=C4C(OCO4)=C3)O)([H])C5=C(C6=C(OCO6)C=C5)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Chelidonine 是白屈菜中的异喹啉生物碱，可导致细胞周期 G2/M停滞，诱导 caspase 依赖和非依赖性的细胞凋亡。具有抗肿瘤和抗病毒活性。 |
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Noureini, S.K., and Wink, M.Transcriptional down regulation of hTERT and senescence induction in HepG2 cells by chelidonineWorld J. Gastroenterol.15(29),3603-3610(2009)
Och, A., Szewczyk, K., Pecio, Ł., et al.UPLC-MS/MS profile of alkaloids with cytotoxic properties of selected medicinal plants of the Berberidaceae and Papaveraceae familiesOxid. Med. Cell. Longev.2017:9369872,(2017)
Habermehl, D., Kammerer, B., Handrick, R., et al.Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathwayBMC Cancer6:14,(2006)
