RWJ 50271
Cat. No.:YN300018
产品名称: | RWJ 50271 |
CAS No.: | 162112-37-0 |
Chemical Name: | N-(3-Hydroxypropyl)-5-methyl-1-[-4-[3-(trifluoromethyl)phenyl)]-2-thiazolyl]-1H-pyrazole-4-carboxamide |
Synonyms: | |
分子量: | 410.41 |
分子式: | C₁₈H₁₇F₃N₄O₂S |
SMILES: | CC1=C(C(NCCCO)=O)C=NN1C2=NC(C3=CC(C(F)(F)F)=CC=C3)=CS2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | RWJ 50271 是一种选择性的LFA-1/ICAM-1相互作用抑制剂,IC50值为 5.0 μM (HL60 cells)。RWJ 50271 抑制 LFA-1/ICAM-1 介导的细胞粘附。 |
IC50和靶点: | |
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Clinical Trial: | |
Solvent & Solubility: |
Sanfolippo, P. J., et al.: J. Med. Chem., 38, 1057 (1995)