Pyrintegrin
Cat. No.：YN300027
CAS No. ：1228445-38-2
| 产品名称: | Pyrintegrin |
| CAS No.: | 1228445-38-2 |
| Chemical Name: | N-(cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]-benzenesulfonamide |
| Synonyms: | Pyrintegrin; PTN; |
| 分子量: | 451.54 |
| 分子式: | C₂₃H₂₅N₅O₃S |
| SMILES: | O=S(C1=CC=C(NC2=NC=CC(N3CCCC4=C3C=CC(O)=C4)=N2)C=C1)(NCC5CC5)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pyrintegrin 是一种 β1 整合素 (β1-integrin) 激动剂，也是一种 2,4-二取代的嘧啶，可促进胚胎干细胞存活。Pyrintegrin 能增强细胞-细胞外基质 (ECM) 粘附介导的整联蛋白信号传导。Pyrintegrin 可用作足细胞保护剂，并具有强大的成脂作用。 |
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Xu, Y., Zhu, X., Hahm, H.S., et al.Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small moleculesProc. Natl. Acad. Sci. USA107(18),8129-8134(2010)
