ATN-161 trifluoroacetate salt
Cat. No.：YN300030
CAS No. ：904763-27-5
| 产品名称: | ATN-161 trifluoroacetate salt |
| CAS No.: | 904763-27-5 |
| Chemical Name: | 1-acetyl-L-prolyl-L-histidyl-L-seryl-L-cysteinyl-L-aspartamide, monotrifluoroacetate salt |
| Synonyms: | ATN-161 TFA salt |
| 分子量: | 711.67 |
| 分子式: | C₂₅H₃₆F₃N₉O₁₀S |
| SMILES: | FC(F)(C(O)=O)F.O=C(N)C[C@@H](C(N)=O)NC([C@H](CS)NC([C@H](CO)NC([C@H](CC1=CNC=N1)NC([C@H]2N(C(C)=O)CCC2)=O)=O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ATN-161 trifluoroacetate salt 是一种新型integrin α5β1拮抗剂，在肝转移模型小鼠模型中，抑制血管生成。 |
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Khalili, P., Arakelian, A., Chen, G., et al.A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivoMol. Cancer Ther.5(9),2271-2280(2006)
Beddingfield, B.J., Iwanaga, N., Chapagain, P.P., et al.The integrin binding peptide, ATN-161, as a novel therapy for SARS-CoV-2 infectionJACC Basic Transl. Sci.6(1),1-8(2021)
Wang, W., Wang, F., Lu, F., et al.The antiangiogenic effects of integrin α5β1 inhibitor (ATN-161) in vitro and in vivoInvest. Ophthalmol. Vis. Sci.52(10),7213-7220(2011)
Edwards, D.N., Salmeron, K., Lukins, D.E., et al.Integrin α5β1 inhibition by ATN-161 reduces neuroinflammation and is neuroprotective in ischemic strokeJ. Cereb. Blood Flow Metab.40(8),1695-1708(2020)
