BIO-1211
Cat. No.：YN300033
| 产品名称: | BIO-1211 |
| CAS No.: | 187735-94-0 |
| Chemical Name: | N-[2-[4-[[[(2-Methylphenyl)amino]carbonyl]amino]phenyl]acetyl]-L-leucyl-L-α-aspartyl-L-valyl-L-proline |
| Synonyms: | BIO-1211;BIO 1211 |
| 分子量: | 708.80 |
| 分子式: | C₃₆H₄₈N₆O₉ |
| SMILES: | O=C(O)[C@H]1N(C([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC(CC2=CC=C(NC(NC3=CC=CC=C3C)=O)C=C2)=O)=O)=O)=O)CCC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BIO-1211 是高度选择性的、具有口服活性的α4β1 (VLA-4)抑制剂，其对 α4β1 和 α4β7 的IC50值分别为 4 nM 和 2 μM。 |
| IC50和靶点: | [{name:"α4β1:4 nM (IC50)"},{name: "α4β7:2 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Karanam, B. V., et al.: Xenobiotica, 37, 487 (2007)
Chiba, J., et al.: Bioorg. Med. Chem. Lett., 15, 1259 (2005)
