Eptifibatide
Cat. No.：YN300058
CAS No. ：188627-80-7
| 产品名称: | Eptifibatide |
| CAS No.: | 188627-80-7 |
| Chemical Name: | N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic (1→6)-disulfide |
| Synonyms: | 依替巴肽 |
| 分子量: | 831.96 |
| 分子式: | C₃₅H₄₉N₁₁O₉S₂ |
| SMILES: | O=C(N(CCC1)[C@]1([H])C(N[C@@H](CSSCCC2=O)C(N)=O)=O)[C@](NC([C@@H](NC(CNC([C@@H](N2)CCCCNC(N)=N)=O)=O)CC(O)=O)=O)([H])CC3=CNC4=CC=CC=C34 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Eptifibatide 是一种环状七肽，为glycoprotein IIb/IIIa受体抑制剂，具有抗血小板活性。 |
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Harder, S., Klinkhardt, U., Graff, J., et al.In vitro dose response to different GPIIb/IIIa-antagonists: Inter-laboratory comparison of various platelet function testsThromb. Res.102(1),39-48(2001)
Moser, M., Bertram, U., Peter, K., et al.Abciximab, eptifibatide, and tirofiban exhibit dose-dependent potencies to dissolve platelet aggregatesJ. Cardiovasc. Pharmacol.41(4),586-592(2003)
Scarborough, R.M.Development of eptifibatideAm. Heart J.138(6 Pt 1),1093-1104(1999)
Ciborowski, M., and Tomasiak, M.The in vitro effect of eptifibatide, a glycoprotein IIb/IIIa antagonist, on various responses of porcine blood plateletsActa Pol. Pharm.66(3),235-242(2009)
Zhou, X., Wu, X., Sun, H., et al.Efficacy and safety of eptifibatide versus tirofiban in acute coronary syndrome patients: A systematic review and meta-analysisJ. Evid. Based Med.10(2),136-144(2017)
