PRN694
Cat. No.:YN440222
产品名称: | PRN694 |
CAS No.: | 1575818-46-0 |
Chemical Name: | |
Synonyms: | PRN694|PRN-694 |
分子量: | 543.67 |
分子式: | C₂₈H₃₅F₂N₅O₂S |
SMILES: | O=C(C1=CC=C(C(F)F)S1)NC2=NC3=CC(CN[C@@H](C)C(C)(C)C)=CC=C3N2C[C@@H]4N(C(C=C)=O)CCC4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PRN694 是一种不可逆的,高效选择性的,有效共价结合的白介素 2 诱导细胞激酶ITK、 静息淋巴细胞激酶RLK双重抑制剂,抑制 ITK、RLK 的IC50分别为 0.3 nM 和 1.4 nM。PRN694 延长靶向停留时间,使效应细胞在体内外持久衰减。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |