TyK2-IN-2
Cat. No.：YN340026
CAS No. ：2098466-94-3
| 产品名称: | TyK2-IN-2 |
| CAS No.: | 2098466-94-3 |
| Chemical Name: | |
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| 分子量: | 310.35 |
| 分子式: | C₁₆H₁₈N₆O |
| SMILES: | CNC1=CC(NC2=CC(C)=CC(C)=C2)=NN3C1=NC=C3C(N)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TyK2-IN-2 (Compoud 18) 是一种有效的选择性TYK2抑制剂，对TYK2 JH2，IL-23和IFNα的IC50值分别为 7 nM，0.1 μM 和 0.05 μM。TyK2-IN-2 还抑制磷酸二酯酶 4 (PDE4)，其IC50为 62 nM。TyK2-IN-2 可用于炎症及自身免疫病的研究。 |
| IC50和靶点: | [{name:"Tyk2 JH2:7 nM (IC50)"},{name: "PDE4:62 nM (IC50)"}] |
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