FM-381
Cat. No.：YN340032
CAS No. ：2226521-65-7
| 产品名称: | FM-381 |
| CAS No.: | 2226521-65-7 |
| Chemical Name: | |
| Synonyms: | FM381 |
| 分子量: | 428.49 |
| 分子式: | C₂₄H₂₄N₆O₂ |
| SMILES: | CN(C(/C(C#N)=C/C1=CC=C(C2=NC3=CN=C(NC=C4)C4=C3N2C5CCCCC5)O1)=O)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | FM-381 是有效，共价，可逆的JAK3抑制剂，靶向 Cys909 位点。FM-381 对 JAK3 的IC50值为127 pM，选择性分别比 JAK1，JAK2 和 TYK2 高 410，2700 和 3600 倍。 |
| IC50和靶点: | [{name:"JAK3:127 pM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
