JAK/HDAC-IN-1
Cat. No.：YN340106
CAS No. ：2284621-75-4
| 产品名称: | JAK/HDAC-IN-1 |
| CAS No.: | 2284621-75-4 |
| Chemical Name: | |
| Synonyms: | JAK/HDAC-IN-1; MUN21754; MUN-21754; MUN 21754; |
| 分子量: | 450.32 |
| 分子式: | C₁₉H₂₁Cl₂N₇O₂ |
| SMILES: | ClC1=CC=C(NC2=NC(NC3=CN(CCCCCC(NO)=O)N=C3)=NC=C2Cl)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JAK/HDAC-IN-1 是一种有效的JAK2/HDAC双重抑制剂，在一些血液学细胞系中具有抗增殖和促凋亡作用。JAK/HDAC-IN-1 对 JAK2 和 HDAC 的IC50值分别为 4 和 2 nM。 |
| IC50和靶点: | [{name:"JAK2:4 nM (IC50)"},{name: "JAK1:4.8 nM (IC50)"},{name: "JAK3:7.4 nM (IC50)"},{name: "Tyk2:49 nM (IC50)"},{name: "HDAC:2 nM (IC50)"},{name: "HDAC2:14 nM (IC50)"},{name: "HDAC6:120 nM (IC50)"},{name: "HDAC8:2470 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
