PF-06826647
Cat. No.：YN340107
CAS No. ：2127109-84-4
| 产品名称: | PF-06826647 |
| CAS No.: | 2127109-84-4 |
| Chemical Name: | |
| Synonyms: | PF-06826647,Tyk2-IN-8 |
| 分子量: | 383.41 |
| 分子式: | C₂₀H₁₇N₉ |
| SMILES: | N#CC[C@@]1(N2N=CC(C3=NC(C4=CN(C)N=C4)=CN5C3=CC=N5)=C2)C[C@@H](C#N)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-06826647 是一种口服活性和选择性TYK2抑制剂 (IC50=17 nM)，与 TYK2 催化活性 JH1 结构域结合。PF-06826647 对 JAK1 (IC50=383 nM) 和 JAK2 (74 nM)具有选择性。PF-06826647 可用于银屑病、溃疡性结肠炎和化脓性汗腺炎的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
