Oclacitinib maleate
Cat. No.：YN340138
CAS No. ：1640292-55-2
| 产品名称: | Oclacitinib maleate |
| CAS No.: | 1640292-55-2 |
| Chemical Name: | |
| Synonyms: | 奥拉替尼马来酸盐; PF-03394197 maleate |
| 分子量: | 453.51 |
| 分子式: | C₁₉H₂₇N₅O₆S |
| SMILES: | O=S(C[C@H]1CC[C@H](N(C)C2=C3C(NC=C3)=NC=N2)CC1)(NC)=O.O=C(O)/C=C\C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Oclacitinib maleate (PF-03394197 maleate) 是一种新型JAK抑制剂。Oclacitinib maleate (PF-03394197 maleate) 抑制JAK1最有效，IC50为 10 nM。 |
| IC50和靶点: | [{name:"JAK1:10 nM (IC50)"},{name: "JAK2:18 nM (IC50)"},{name: "Tyk2:84 nM (IC50)"},{name: "JAK3:99 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
(1) Gonzales, A.J., et al.: J. Vet. Pharmacol. Ther., 37, 317 (2014) & (2) Collard, W. T., et al.: J Vet Pharmacol Ther. 37, 279 (2014)
