GLPG0634 analog
Cat. No.:YN340154
产品名称: | GLPG0634 analog |
CAS No.: | 1206101-20-3 |
Chemical Name: | GLPG0634 |
Synonyms: | GLPG0634 analogue |
分子量: | 410.43 |
分子式: | C₂₃H₁₈N₆O₂ |
SMILES: | O=C(C1CC1)NC2=NN3C(C4=CC=C(OCC5=CC=C(C#N)N=C5)C=C4)=CC=CC3=N2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GLPG0634 (analog) 是一种 JAK 广谱性抑制剂,对 JAK1/JAK2/JAK3 的IC50值为 50-200 nM。 |
IC50和靶点: | [{name:"JAK1:<100 nM (IC50)"},{name: "JAK2:<100 nM (IC50)"},{name: "JAK3:<100 nM (IC50)"},{name: "Tyk2:<100 nM (IC50)"}] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Vanhoutte, F., et al.: Galapagos NV, www.glpg.com. (2011)