SB1317
Cat. No.：YN340166
CAS No. ：937270-47-8
| 产品名称: | SB1317 |
| CAS No.: | 937270-47-8 |
| Chemical Name: | 14-methyl-20-oxa-5,7,14,27-tetraazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene |
| Synonyms: | TG02 |
| 分子量: | 372.46 |
| 分子式: | C₂₃H₂₄N₄O |
| SMILES: | CN1CC2=CC(NC3=NC(C4=CC(OCC/C=C/C1)=CC=C4)=CC=N3)=CC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SB1317 是一种有效的CDK2，JAK2和FLT3抑制剂，IC50分别为 13，73 和 56 nM。 |
| IC50和靶点: | [{name:"CDK2:13 nM (IC50)"},{name: "JAK2:73 nM (IC50)"},{name: "FLT3:56 nM (IC50)"}] |
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| Solvent & Solubility: |
Goh, K.C., Novotny-Diermayr, V., Hart, S., et al.TG02, a novel oral multi-kinase inhibitor of CDKs, JAK2 and FLT3 with potent anti-leukemic propertiesLeukemia26(2),236-243(2012)
