JANEX-1
Cat. No.：YN340177
| 产品名称: | JANEX-1 |
| CAS No.: | 202475-60-3 |
| Chemical Name: | 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol |
| Synonyms: | WHI-P131; Jak3 inhibitor I |
| 分子量: | 297.31 |
| 分子式: | C₁₆H₁₅N₃O₃ |
| SMILES: | OC1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JANEX-1 (WHI-P131) 是一种有效的特异性JAK3抑制剂，Ki为 2.3 μM，IC50为 78 μM，JANEX-1 不抑制 JAK1 和 JAK2。 |
| IC50和靶点: | [{name:"JAK3:78 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Sudbeck, E.A., Liu, X.P., Narla, R.K., et al.Structure-based design of specific inhibitors of Janus kinase 3 as apoptosis-inducing antileukemic agentsClin. Cancer Res.5(6),1569-1582(1999)
