Ilginatinib maleate
Cat. No.：YN340220
CAS No. ：1354799-87-3
| 产品名称: | Ilginatinib maleate |
| CAS No.: | 1354799-87-3 |
| Chemical Name: | |
| Synonyms: | NS-018 maleate |
| 分子量: | 505.50 |
| 分子式: | C₂₅H₂₄FN₇O₄ |
| SMILES: | CN1N=CC(C2=CC(N[C@H](C3=CC=C(F)C=C3)C)=NC(NC4=NC=CN=C4)=C2)=C1.O=C(O)/C=C\C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ilginatinib maleate (NS-018 maleate) 是一种高度有效的，可口服的JAK2抑制剂，IC50值为 0.72 nM，对其选择性是对 JAK1 的 46 倍 (IC50, 33 nM)，JAK3 的 54 倍 (IC50, 39 nM)，以及 Tyk2 的 22 倍 (IC50, 22 nM)。 |
| IC50和靶点: | [{name:"JAK2:0.72 nM (IC50)"},{name: "Tyk2:22 nM (IC50)"},{name: "JAK1:33 nM (IC50)"},{name: "JAK3:39 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
