Tofacitinib
Cat. No.:YN340232
CAS No. :477600-75-2
产品名称: | Tofacitinib |
CAS No.: | 477600-75-2 |
Chemical Name: | |
Synonyms: | 托法替尼; Tasocitinib; CP-690550 |
分子量: | 312.37 |
分子式: | C₁₆H₂₀N₆O |
SMILES: | O=C(CC#N)N1C[C@H](N(C2=C3C(NC=C3)=NC=N2)C)[C@H](C)CC1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tofacitinib是JAK3/2/1抑制剂,IC50分别为1,20 和 112 nM。 |
IC50和靶点: | [{name:"JAK3:1 nM (IC50)"},{name: "JAK2:20 nM (IC50)"},{name: "JAK1:112 nM (IC50)"},{name: "Rock-II:3400 nM (IC50)"},{name: "Lck:3870 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |