SU3327
Cat. No.：YN350050
CAS No. ：40045-50-9
| 产品名称: | SU3327 |
| CAS No.: | 40045-50-9 |
| Chemical Name: | 5-[(5-nitro-2-thiazolyl)thio]-1,3,4-thiadiazol-2-amine |
| Synonyms: | |
| 分子量: | 261.30 |
| 分子式: | C₅H₃N₅O₂S₃ |
| SMILES: | NC1=NN=C(S1)SC2=NC=C([N+]([O-])=O)S2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SU3327 是一种有效的，选择性的且具有底物竞争性的JNK抑制剂，IC50为 0.7 μM。SU3327 还以IC50值为 239 nM 抑制JNK和 JIP 之间的蛋白相互作用。SU3327 对 p38α 和 Akt 激酶的活性较低。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
De, S.K., Stebbins, J.L., Chen, L.-H., et al.Design, synthesis, and structure-activity relationship of substrate competitive, selective, and in vivo active triazole and thiadiazole inhibitors of the c-Jun N-terminal kinaseJ. Med. Chem.52(7),1943-1952(2009)
Stokes, J.M., Yang, K., Swanson, K., et al.A deep learning approach to antibiotic discoveryCell180(4),688-702(2020)
