AS601245
Cat. No.：YN350066
CAS No. ：345987-15-7
| 产品名称: | AS601245 |
| CAS No.: | 345987-15-7 |
| Chemical Name: | a-[2-[[2-(3-pyridinyl)ethyl]amino]-4-pyrimidinyl]-2-benzothiazoleacetonitrile |
| Synonyms: | AS-601245 |
| 分子量: | 372.45 |
| 分子式: | C₂₀H₁₆N₆S |
| SMILES: | N#CC(C1=CC=NC(NCCC2=CC=CN=C2)=N1)C3=NC4=CC=CC=C4S3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AS601245 是一种细胞可渗透性的JNK抑制剂，抑制hJNK1，hJNK2和hJNK3，IC50分别为 150, 220 和 70 nM。 |
| IC50和靶点: | [{name:"hJNK1:150 nM (IC50)"},{name: "hJNK2:220 nM (IC50)"},{name: "hJNK3:70 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
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Tu, Y.F., Tsai, Y.S., Wang, L.W., et al.Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivationJ. Neuroinflammation8:40,(2011)
