JNK-IN-7
Cat. No.：YN350165
CAS No. ：1408064-71-0
| 产品名称: | JNK-IN-7 |
| CAS No.: | 1408064-71-0 |
| Chemical Name: | 3-[[4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide |
| Synonyms: | JNK inhibitor |
| 分子量: | 493.56 |
| 分子式: | C₂₈H₂₇N₇O₂ |
| SMILES: | O=C(C1=CC(NC(/C=C/CN(C)C)=O)=CC=C1)NC(C=C2)=CC=C2NC3=NC=CC(C4=CN=CC=C4)=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JNK-IN-7 是一种有效的JNK抑制剂，抑制JNK1，JNK2和JNK3，IC50分别为 1.5，2 和 0.7 nM。 |
| IC50和靶点: | [{name:"JNK3:0.7 nM (IC50)"},{name: "JNK1:1.5 nM (IC50)"},{name: "JNK2:2 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Zhang, T., Inesta-Vaquero, F., Niepel, M., et al.Discovery of potent and selective covalent inhibitors of JNKChem. Biol.19(1),140-154(2012)
