DB07268
Cat. No.：YN350167
CAS No. ：929007-72-7
| 产品名称: | DB07268 |
| CAS No.: | 929007-72-7 |
| Chemical Name: | 2-[[2-[(3-hydroxyphenyl)amino]-4-pyrimidinyl]amino]-benzamide |
| Synonyms: | Benzamide, 2-[[2-[(3-hydroxyphenyl)amino]-4-pyrimidinyl]amino]-;DB07268;DB-07268 |
| 分子量: | 321.33 |
| 分子式: | C₁₇H₁₅N₅O₂ |
| SMILES: | O=C(N)C1=CC=CC=C1NC2=NC(NC3=CC=CC(O)=C3)=NC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | DB07268 是一种有效的选择性JNK1抑制剂，IC50值为 9 nM。 |
| IC50和靶点: | [{name:"JNK1:9 nM (IC50)"},{name: "CHK1:0.82 μM (IC50)"},{name: "PAK4:5.5 μM (IC50)"},{name: "AKT1:15 μM (IC50)"},{name: "ERK2:25 μM (IC50)"}] |
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| Solvent & Solubility: |
Schütz, H.Benzodiazepines: A handbook. Basic data, analytical methods, pharmacokinetics, and comprehensive literature,439(1982)
Simon-Szabó, S., Kokas, M., Greff, Z., et al.Novel compounds reducing IRS-1 serine phosphorylation for treatment of diabetesBioorg. Med. Chem. Lett26(2),424-428(2016)
