TCS JNK 5a
Cat. No.:YN350172
CAS No. :312917-14-9
产品名称: | TCS JNK 5a |
CAS No.: | 312917-14-9 |
Chemical Name: | N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide |
Synonyms: | JNK Inhibitor IX |
分子量: | 332.42 |
分子式: | C₂₀H₁₆N₂OS |
SMILES: | O=C(C1=C2C=CC=CC2=CC=C1)NC3=C(C#N)C(CCCC4)=C4S3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TCS JNK 5a 是一种有效的JNK3抑制剂,pIC50为 6.7。TCS JNK 5a 也抑制JNK2,pIC50为 6.5。 |
IC50和靶点: | [{name:"JNK3:6.7 (pIC50)"},{name: "JNK2:6.5 (pIC50)"}] |
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Solvent & Solubility: |
Angell, R.M., Atkinson, F.L., Brown, M.J., et al.N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3Bioorg. Med. Chem. Lett.17(5),1296-1301(2007)