Anisomycin
Cat. No.：YN350194
CAS No. ：22862-76-6
| 产品名称: | Anisomycin |
| CAS No.: | 22862-76-6 |
| Chemical Name: | 2-[(4-methoxyphenyl)methyl]-3-acetate-(2R,3S,4S)-3,4-pyrrolidinediol |
| Synonyms: | 茴香霉素; Flagecidin; Wuningmeisu C |
| 分子量: | 265.31 |
| 分子式: | C₁₄H₁₉NO₄ |
| SMILES: | O[C@@H]1[C@@H](OC(C)=O)[C@@H](CC2=CC=C(OC)C=C2)NC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Anisomycin是一种有效的蛋白质合成抑制剂，它通过抑制肽基转移酶80核糖体系统干扰蛋白质和DNA合成。Anisomycin 是一种JNK激活剂，可增强磷酸化JNK。Anisomycin 是从灰链霉菌中分离出的一种细菌抗生素。 |
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Grollman, A.P.Inhibitors of protein biosynthesisJ. Biol. Chem.242(13),3226-3233(1967)
Xing, F., Yu, Z., Liu, J., et al.Anisomycin inhibits the behaviors of T cells and the allogeneic skin transplantation in miceJ. Immunother.31(9),858-870(2008)
Mawji, I.A., Simpson, C.D., Gronda, M., et al.A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesisCancer Res.67(17),8307-8315(2007)
