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Isovitexin

Cat. No.:YN350234

  • CAS No. :38953-85-4

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Isovitexin
      CAS No.: 38953-85-4
      Chemical Name: 6-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
      Synonyms:异牡荆黄素; Saponaretin; Homovitexin
      分子量:432.38
      分子式:C₂₁H₂₀O₁₀
      SMILES:OC1=C(C2=O)C(OC(C3=CC=C(O)C=C3)=C2)=CC(O)=C1[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Isovitexin 是从亚洲水稻种得到的黄酮类物质,具有抗氧化、抗炎的活性;Isovitexin 作用与JNK1/2的抑制剂类似,能够抑制NF-κB的活化。
      IC50和靶点:
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      Clinical Trial:
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    • He, M., Min, J.-W., Kong, W.-L., et al.A review on the pharmacological effects of vitexin and isovitexinFitoterapia115,74-85(2016)

      Zhang, J., Yuan, K., Zhou, W.-L., et al.Studies on the active components and antioxidant activities of the extracts of Mimosa pudica Linn. from southern ChinaPharmacogn. Mag.7(25),35-39(2011)

      Mohammed, R.S., Zeid, A.H.A., Hawary, S.S.E., et al.Flavonoid constituents, cytotoxic and antioxidant activities of Gleditsia triacanthos L. leavesSaudi J. Biol. Sci.21(6),547-553(2014)

      Lv, H., Yu, Z., Zheng, Y., et al.Isovitexin exerts anti-inflammatory and anti-oxidant activities on lipopolysaccharide-induced acute lung injury by inhibiting MAPK and NF-κB and activating HO-1/Nrf2 pathways.Int. J. Biol. Sci.12(1),72-86(2016)

      Guimarães, C.C.O., D.D., Valdevite, M., Fachin Saltoratto, A.L., et al.The glycosylated flavonoids vitexin, isovitexin, and quercetrin isolated from Serjania erecta Radlk (Sapindaceae) leaves protect PC12 cells against amyloid-β25-35 peptide-induced toxicityFood Chem. Toxicol.86,88-94(2015)

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