Actein
Cat. No.：YN350261
| 产品名称: | Actein |
| CAS No.: | 18642-44-9 |
| Chemical Name: | (3β,12β,16β,23R,24R,25S,26S)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-26-hydroxy-9,19-cyclolanostan-3-yl β-D-Xylopyranoside; 9,19-Cyclolanostane β-D-xylopyranoside Deriv; Spiro[5H-cyclopropa[1',8'a]naphth[2',1':4,5]indeno[2,1-b]pyran-10(2H),2'-[3,6]dioxa |
| Synonyms: | 黄肉楠碱 |
| 分子量: | 676.83 |
| 分子式: | C₃₇H₅₆O₁₁ |
| SMILES: | C[C@]12[C@@]3([H])[C@@]4(C[C@@H](OC(C)=O)[C@@]1([C@]5([H])[C@](O[C@]6([C@H]7[C@]([C@@H](O)O6)(C)O7)C[C@H]5C)([H])C2)C)[C@@]8([C@@](C(C)([C@@H](O[C@@]9([H])[C@@H]([C@H]([C@H](O)CO9)O)O)CC8)C)([H])CC3)C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Actein 是从Cimicifuga foetida的根茎中分离的三萜糖苷。Actein 通过促进ROS/JNK活化和钝化人膀胱癌中的AKT途径来抑制细胞增殖，诱导自噬和凋亡。Actein 在体内几乎没有毒性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Findeis, M. et al.: ACS. Chem. Neurosci., 3, 941 (2012)
Einbond, L. et al.: Fund. Clin. Pharm., 23, 311 (2009)
