T56-LIMKi
Cat. No.:YN290454
CAS No. :924473-59-6
产品名称: | T56-LIMKi |
CAS No.: | 924473-59-6 |
Chemical Name: | 3-methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide |
Synonyms: | T5601640 |
分子量: | 389.33 |
分子式: | C₁₉H₁₄F₃N₃O₃ |
SMILES: | O=C(C1=CC(C)=NO1)NC2=CC=CC(C(NC3=CC=CC(C(F)(F)F)=C3)=O)=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | T56-LIMKi是选择性的LIMK2抑制剂。抑制Panc-1细胞生长的IC50值为35.2 μM。 |
IC50和靶点: | |
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Mashiach-Farkash, E., Rak, R., Elad-Sfadia, G., et al.Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeletonOncotarget3(6),629-639(2012)
Rak, R., Haklai, R., Elad-Tzfadia, G., et al.Novel LIMK2 Inhibitor Blocks Panc-1 Tumor Growth in a mouse xenograft modelOncoscience1(1),39-48(2014)