AS2717638
Cat. No.：YN320482
CAS No. ：2148339-28-8
| 产品名称: | AS2717638 |
| CAS No.: | 2148339-28-8 |
| Chemical Name: | 6,7-dimethoxy-2-(5-methyl-1,2-benzisoxazol-3-yl)-4-(1-piperidinylcarbonyl)-1(2H)-isoquinolinone |
| Synonyms: | |
| 分子量: | 447.48 |
| 分子式: | C₂₅H₂₅N₃O₅ |
| SMILES: | O=C1N(C2=NOC3=C2C=C(C)C=C3)C=C(C(N4CCCCC4)=O)C5=C1C=C(OC)C(OC)=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AS2717638 是一种具有口服生物活性的，选择性的溶血磷脂酸受体5 (LPA5)的拮抗剂，其对 hLPA4 的IC50值为38 nM。AS2717638 还能显著改善 PGE2、PGF2α以及AMPA 诱导的异位疼痛。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Murai, N., Hiyama, H., Kiso, T., et al.Analgesic effects of novel lysophosphatidic acid receptor 5 antagonist AS2717638 in rodentsNeuropharmacology126,97-107(2017)
