GSK2018682
Cat. No.：YN321227
CAS No. ：1034688-30-6
| 产品名称: | GSK2018682 |
| CAS No.: | 1034688-30-6 |
| Chemical Name: | 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-1H-indole-1-butanoic acid |
| Synonyms: | GSK-2018682,GSK 2018682，GSK2018682 |
| 分子量: | 440.88 |
| 分子式: | C₂₂H₂₁ClN₄O₄ |
| SMILES: | O=C(O)CCCN1C=CC2=C1C=CC=C2C3=NOC(C4=CC(Cl)=C(OC(C)C)N=C4)=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK2018682 是一种S1P1和S1P5 receptor的激动剂，pEC50值分别为 7.7 和 7.2，对 S1P2, S1P3 或 S1P4 没有明显的激动活性，可用于多发性硬化的研究。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Xu, J., Gray, F., Henderson, A., et al.Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine-1-phosphate receptor modulator, in healthy volunteersClin. Pharmacol. Drug Dev.3(3),170-178(2014)
