TY-52156
Cat. No.：YN321243
CAS No. ：934369-14-9
| 产品名称: | TY-52156 |
| CAS No.: | 934369-14-9 |
| Chemical Name: | N-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidic acid, 2-(4-chlorophenyl)hydrazide |
| Synonyms: | TY52156;TY 52156 |
| 分子量: | 364.27 |
| 分子式: | C₁₈H₁₉Cl₂N₃O |
| SMILES: | ClC1=CC=C(/N=C(NNC2=CC=C(Cl)C=C2)/C(C(C)(C)C)=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TY-52156 是一种有效、选择性的S1P3受体拮抗剂，Ki值为 110 nM。 |
| IC50和靶点: | |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Murakami, A., Takasugi, H., Ohnuma, S., et al.Sphingosine 1-phosphate (S1P) regulates vascular contraction via S1P3 receptor: Investigation based on a new S1P3 receptor antagonistMol. Pharmacol.77(4),704-713(2016)
Hirata, N., Yamada, S., Shoda, T., et al.Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activationNat. Commun.5:4806,(2014)
